Publications


 

1– Synthesis and Activity of Juvenile Hormone Analogues.

     J. B. Rodriguez, E. G. Gros* and A. M. Stoka.

     Z. Naturforsch. B 1988, 43, 1038–1042.

 

2– Synthesis and Activity of Juvenile Hormone Analogues. Part II.

     J. B. Rodriguez, E. G. Gros* and A. M. Stoka.

     Z. Naturforsch. B 1989, 44, 983–987.

 

3– A Convenient Method for the Preparation of Juvenile Hormone III.

     J. B. Rodriguez and E. G. Gros*.

     Z. Naturforsch. B 1990, 45, 93–95.

 

4– Biological Activity of Synthetic Juvenile Hormone Analogues for Trypanosoma cruzi.

     A. M. Stoka, C. Rivas, E. Segura, J. B. Rodriguez and E. G. Gros*.

     Z. Naturforsch. B 1990, 45, 96–98.

 

5– Synthesis and Biological Activity of Synthetic Juvenile Hormone Analogues for Trypanosoma cruzi.

     J. B. Rodriguez, E. G. Gros* and A. M. Stoka.

     Bioorg. Med. Chem. Lett. 1991, 1, 679–682.

 

6– Preparation of Enantiomerically Pure Juvenile Hormone Analogues.

     J. B. Rodriguez and E. G. Gros*.

     Anal. Asoc. Quim. Arg. 1992, 80, 139–148. (Dedicado al Dr. A. O. M. Stoppani).

 

7– Preparation of 2(R) and 2(S) Methyl-2-Methylglycerates.

     J. B. Rodriguez, S. P. Markey and H. Ziffer.

     Tetrahedron : Asymmetry 1993, 4, 101–108.

 

8– Gas Chromatographic-Mass Spectrometric Method for the Assessment of Oxidative Damage to Double

     Stranded DNA by Quantification Thymine Glycol Residues.

     S. P. Markey,* C. J. Markey, T.-C. L. Wang and J. B. Rodriguez.

     J. Am. Soc. Mass Spectrom. 1993, 4, 336–342.

 

9– Synthesis of Cyclopropane-fused Dideoxycarbocyclic Nucleosides Structurally Related to Neplanocin C.

     J. B. Rodriguez, V. E. Marquez,* M. C. Nicklaus and J. J. Barchi, Jr.

     Tetrahedron Lett. 1993, 34, 6233–6236.

 

10– Effects of Juvenile Hormone on Mammalian Steroidogenesis.

     E. A. Vladusic,* L. E. Bussmann, P. E. Visconti, A. M. Stoka, J. B. Rodriguez, E. G. Gros and E. H.

     Charreau.

     J. Steroid. Biochem. Mol. Biol. 1994, 50, 181–187.

 

11– Conformationally Locked Nucleosides Analogues.  Synthesis of Dideoxycarbocyclic Nucleosides Analogues

     Structurally Related to Neplanocin C.

     J. B. Rodriguez, V. E. Marquez,* M. C. Nicklaus, H. Mitsuya and J. J. Barchi, Jr.

     J. Med. Chem. 1994, 37, 3389–3399.

 

12– Ritter Reaction on Terpenoids. III. Stereospecific Preparation of Bicyclic[3.3.1]Substituted Piperidines.

     W. N. Samaniego, A. Baldessari, M. A. Ponce, J. B. Rodriguez,* E. G. Gros, J. A. Caram and C. M.

     Marschoff.

     Tetrahedron Lett. 1994, 35, 6967–6970.

 

13– Effects of Juvenile Hormone Analogues (JHA) on the Development of Trypanosoma cruzi.

     L. Fichera, M. Esteva, Z. Wimmer, J. B. Rodriguez and E. G. Gros*.

     Z. Naturforsch. C 1995, 50, 578–580.

 

14– Design, Synthesis and anti-Trypanosoma cruzi Evaluation of a New Class of Cell Growth Inhibitors

    Structurally Related to Fenoxycarb.

    A. J. Schvartzapel, L. Fichera, M. Esteva, J. B. Rodriguez and E. G. Gros*.

    Helv. Chim. Acta 1995, 78, 1207–1214.

 

15– Ritter Reaction on Terpenoids. IV. Remarkable Tendency to Produce 3-Aza-bicyclo [3.3.1] non-2-ene

    Systems from Mono and Sesquiterpenes.

    J. B. Rodriguez,* E. G. Gros, J. A. Caram and C. M. Marschoff.

    Tetrahedron Lett. 1995, 36, 7825–7828.

 

16– Recent Developments in the Control of Trypanosoma cruzi, the Causative Agent for Chagas' Disease.

    J. B. Rodriguez* and E. G. Gros.

    Curr. Med. Chem. 1995, 2, 723–742.

 

17– The Sterols of Cucurbita moschata ("Calabacita") Seed Oil.

    J. B. Rodriguez, E. G. Gros,* M. H. Bertoni and P. Cattaneo.

    Lipids 1996, 31, 1205–1208.

 

18– Biological Evaluation of Two Potent Inhibitors of Trypanosoma cruzi epimastigotes against the Intracellular

    Form of the Parasite.

    J. B. Rodriguez,* L. Zhong, R. Docampo and E. G. Gros.

    Bioorg. Med. Chem. Lett. 1996, 6, 2783–2786.

 

19– Design, Synthesis and Biological Evaluation of New Growth Inhibitors of Trypanosoma cruzi (Epimastigotes).

    A. J. Schvartzapel, L. Zhong, R. Docampo, J. B. Rodriguez* and E. G. Gros.

    J. Med. Chem. 1997, 40, 2314–2322.

 

20– Design, Synthesis and Biological Evaluation of Isoprenoid Derivatives as Inhibitors of Trypanosoma cruzi

    Replication.

    J. B. Rodriguez, E. G. Gros* and A. M. Stoka.

    Anal. Soc. Cient. Argentina 1997, 227, 87–91. (Dedicado al Dr. P. Cattaneo)

 

21 Structure-Activity Relationship of New Growth Inhibitors of Trypanosoma cruzi.

    G. M. Cinque, S. H. Szajnman, L. Zhong, R. Docampo, A. J. Schvartzapel, J. B. Rodriguez* and E. G. Gros.

    J. Med. Chem. 1998, 41, 1540–1554.

 

22– Expeditious Preparation of Aristeromicyn Analogues. Synthesis of 2’,3’-Deoxyaristeromycin.

    M. J. Comin and J. B. Rodríguez.*

    Anal. Asoc. Quim. Arg. 1998, 86, 131–138. (Número homenaje al Dr. E. G. Gros)

 

23– Growth Inhibitory Effect of Juvenile Hormone Analogues on Epimastigotes of Trypanosoma cruzi.

    J. B. Rodriguez,* L. Zhong, R. Docampo, Z. Wimmer, and E. G. Gros.

    Bioorg. Med. Chem. Lett. 1998, 8, 3257–3260.

 

24– Chiral 1,4-Dicarbonyl-2,3-O-Isopropylidene Derivatives. Rapid Racemization on Standing.

    J. B. Rodríguez.

    Tetrahedron 1999, 55, 2157–2170.

 

25– Synthesis of C-5'-nor-Dideoxycarbanucleosides Structurally Related to Neplanocin C.

    M. J. Comin, C. A. Pujol, E. B. Damonte and J. B. Rodríguez*.

    Nucleosides  Nucleotides 1999, 18, 2219–2231.

 

26– Biological Activity of very Potent Antiparasitic Agents Towards T84 Colon Tumor Cells.

    J. B. Rodriguez,* E. Cafferata, T. A. Santa-Coloma and E. G. Gros.

    Rev. Latinoam. Quim. 1999, 27, 51–55.

 

27– Sulfur-containing Derivatives Structurally related to Fenoxycarb are Potent Growth Inhibitors against the

    Intracellular Form of Trypanosoma cruzi.

    J. B. Rodriguez,* R. Docampo and E. G. Gros.

    Int. J. Antimicrob. Agents 2000, 13, 215–218.

   

28 Design and Synthesis of Aryloxyethyl Thiocyanate Derivative as Potent Inhibitors of Trypanosoma cruzi

    Proliferation.

    S. H. Szajnman, W. Yan, B. N. Bailey, R. Docampo, E. Elhalem and J. B. Rodriguez*.

    J. Med. Chem. 2000, 43, 1826–1840.

 

29– First Synthesis of (–)-Neplanocin C.

    M. J. Comin and J. B. Rodriguez*

    Tetrahedron 2000, 56, 4639–4649.

 

30– Bisphosphonates Derived from Fatty Acids are Potent Growth Inhibitors of Trypanosoma cruzi.

    S. H. Szajnman, B. N. Bailey, R. Docampo and J. B. Rodriguez*.

    Bioorg. Med. Chem. Lett. 2001, 11, 789–792.

 

31– Specific Molecular Targets to Control Tropical Diseases.

    J. B. Rodríguez.

    Curr. Pharm. Des. 2001, 7, 1105–1116.

 

32– Enantioselective Synthesis of (+)-Neplanocin F.

    M. J. Comin, J. Leitofuter and J. B. Rodriguez*.

    Tetrahedron 2002, 58, 31293136.

 

33– Design, Synthesis and Biological Evaluation of Aryloxyethyl Thiocyanate Derivatives against Trypanosoma

    cruzi.

    E. Elhalem, B. N. Bailey, R. Docampo, I. Ujváry, S. H. Szajnman and J. B. Rodriguez*.

    J. Med. Chem. 2002, 45, 39843999.

 

34Glutathione-like Tripeptides as Inhibitors of Glutathionylspermidine Synthetase: 1. Substitution of the Glycine

    Carboxylic Acid Group.

    K. Amssoms, S. L. Oza, E. Ravaschino, A. Yamani, A. –M. Lambeir, P. Rajan, G. Bal, J. B. Rodriguez, A. H.

    Fairlamb, K. Augustyns and A. Haemers*.

    Bioorg. Med. Chem. Lett. 2002, 12, 25532556.

 

35 Solubility of Two Stable Iminium Salts in 12 Polar Solvents.

    M. C. Grande, C. R. Barrero, C. M. Marschoff,* J. B. Rodriguez and E. G. Gros.

    J. Chem. Eng. Data 2002, 47, 13371338.

 

36 New Progresses in the Enantioselective Synthesis and Biological Properties of Carbocyclic Nucleosides.

    J. B. Rodríguez* and M. J. Comin.

    Mini Rev. Med. Chem. 2003, 3, 95–114.

 

37 Synthesis of Conformationally Locked Carbocyclic Nucleosides Built on an Oxabicyclo[3.1.0]hexane System.

    M. J. Comin, J. B. Rodriguez, *P. Russ and V. E. Marquez.*.

    Tetrahedron 2003, 59, 295301.

 

38 Mechanism of action of 4-phenoxyphenoxy derivatives against Trypanosoma cruzi, the causative agent of

    Chagas disease.

    J. A. Urbina,* J. L. Concepcion, A. Montalvetti, J. B. Rodriguez and R. Docampo..

    Antimicrob. Agents Chemother. 2003, 47, 20472050.

 

39 Bisphosphonates Derived from Fatty Acids are Potent Inhibitors of Trypanosoma cruzi Farnesyl

    Pyrophosphate Synthase.

    S. H. Szajnman, A. Montalvetti, Y. Wang, R. Docampo and J. B. Rodriguez*.

    Bioorg. Med. Chem. Lett. 2003, 13, 3231–3235.

 

40Synthesis and Biological Evaluation of Glutathione-like Tripeptides against Trypanosoma cruzi.

    E. L. Ravaschino, R. Docampo and J. B. Rodriguez*.

    Arkivoc 2003, Part (x), 298313. Número homenaje Prof. E. Rúveda & Prof. R. Rossi.

 

41 Structural Determinants of Efficacy at A3 Adenosine Receptors: Modification of the Ribose Moiety.

    Z. –G. Gao, L. S. Jeong, H. R. Moon, H. O. Kim, W. J. Choi, D. H. Shin, E. Elhalem, M. J. Comin, N.

    Melman, L. Mamedova, A. S. Gross, J. B. Rodriguez and K. A. Jacobson*.

    Biochem. Pharmacol. 2004, 67, 893901.

 

42 Cerium Ammonium Nitrate: A New Catalyst for Regioselective Protection of Glycols.

    M. J. Comin, E. Elhalem and J. B. Rodríguez*.

    Tetrahedron 2004, 60, 1185111860.

 

43 Synthetic Studies towards the Preparation of (4R,5R)-(–)-3-[(Benzyloxy)methyl]-4,5-O-isopropylidene-

    cyclopenten-2-one. An Important Synthetic Intermediate for Carbanucleosides

    E. Elhalem, M. J. Comin, J. Leitofuter, G. García-Liñares and J. B. Rodriguez*.

    Tetrahedron : Asymmetry 2005, 16, 425–431.

 

44– New Insights into the Chemistry of gem-Bis(phosphonates): Unexpected Rearrangement of Michael-type

    Acceptors.

    S. H. Szajnman, G. García Liñares, P. Moro and J. B. Rodríguez*.

    Eur. J. Org. Chem. 2005, 36873696.

 

45 Synthesis and Biological Evaluation of 1-Amino-1,1-Bisphosphonates Derived from Fatty Acids against

    Trypanosoma cruzi targeting Farnesyl Pyrophosphate Synthase.

    S. H. Szajnman, E. L. Ravaschino, R. Docampo and J. B. Rodriguez*.

    Bioorg. Med. Chem. Lett. 2005, 15, 46854690.

 

46First Synthesis of (+)-Neplanocin B.

    M. J. Comin, S. C. Pellegrinet and J. B. Rodriguez*

    Arkivoc 2005, Part (xii), 205213. Número homenaje Prof. Rosa R. de Lederkremer

 

47 Photoinduced Changes of Absorption and Circular Dichroism in a Chiral Nematic Phase containing a

    Photochromic Fulgide.

    M. Bossi, J. B. Rodriguez and P. Aramendía*.

    J. Photochem. Photobiol. A: Chemistry 2006. 179, 3541.

 

48– Progresses in the Field of Drug Design to Combat Tropical Protozoan Parasitic Diseases.

    G. García Liñares, E. L. Ravaschino and J. B. Rodriguez*.

    Curr. Med. Chem. 2006, 13, 335–360.

.

49 Design, Synthesis and Biological Evaluation of Phosphinopeptides against Trypanosoma cruzi Targeting

    Trypanothione Biosynthesis

    E. L. Ravaschino, R. Docampo and J. B. Rodriguez*.

    J. Med. Chem. 2006, 49, 426435.